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KMID : 0604519940200010037
Journal of the Society of Cosmetic Scientists of Korea
1994 Volume.20 No. 1 p.37 ~ p.51
A Study on the Preparation and Application of Chitosan Microcapsule and Bead
Ha Byung-Jo

Lee Ok-Sub
Abstract
Empty cross-linked chitosan microcapsule was prepared by chemical cross-linking reaction using glutaraldehyde(GA). Chitosan bead was also prepared by coacervation method using sodium hydroxide. The technique involves the formation of a chitosan solution in the discontinuous phase of W/O emulsion. The factors influencing the emulsion stability have been examined to establish optimum conditions Chitosan microcapsules were useful for encapsulation of biological materials, and chitosan bead was useful to prepare the biologically active peptide-bound polysaccharide. As a model compound Gly-His-Lys, cell growth factor, was successfully coupled to chitosan bead.
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